Obesity and Weight Management
Diabetes
Thyroid Diseases
Parathyroid Diseases
Dyslipidaemia (Cholesterol)
Hypertension
Osteoporosis
Adrenal Gland Diseases
Pituitary Diseases
Sleep Disorders and Hormones
Pregnancy and Endocrine Diseases
Dyslipidaemia means abnormal blood lipid levels — most commonly high LDL cholesterol, high triglycerides or low HDL. It is usually silent but accelerates atherosclerosis and raises the risk of heart attack and stroke.
Dr. Demirci co-authored the “Statins” chapter of the TEMD Dyslipidaemia Guidelines (2018, 2019, 2021), served as investigator and consultant in the Turkish National Familial Hypercholesterolaemia Study and was an investigator in the ORION-5 trial of inclisiran.
Individual Targets
There is no single “normal” cholesterol value. LDL targets depend on overall cardiovascular risk — age, smoking, blood pressure, diabetes, kidney function and family history.
Familial Hypercholesterolaemia
An inherited disorder causing very high LDL from childhood and early heart disease if untreated. First-degree relatives should also be screened.
Treatment
Mediterranean-style diet, exercise, weight control and stopping smoking, plus statins — the most proven drugs for reducing cardiovascular events. Ezetimibe, PCSK9 inhibitors or inclisiran may be added when targets are not met. Secondary causes such as hypothyroidism and diabetes are always checked.
Frequently asked questions
Do I need statins for life?
In high-risk patients statins are usually long-term; cholesterol returns to previous levels when they are stopped.
Can diet alone lower cholesterol?
Diet typically lowers LDL by about 10–20%. Higher-risk patients often also need medication.
Content on this website is for information only and does not replace a medical consultation.
