Hypertension affects about one third of adults. In roughly 10% of patients a treatable underlying cause exists, and many of these causes are hormonal.
Endocrine Causes
- Primary aldosteronism – the most common hormonal cause, often under-diagnosed
- Pheochromocytoma / paraganglioma – episodic hypertension, headache, palpitations, sweating
- Cushing's syndrome
- Thyroid and parathyroid disorders, acromegaly, sleep apnoea
Who Should Be Screened?
Hypertension starting before age 40, resistant hypertension despite three or more drugs, low potassium, episodic symptoms, an incidental adrenal mass or a family history of early stroke.

Management
Accurate diagnosis with home or 24-hour ambulatory monitoring, salt reduction, weight control, exercise and appropriate medication — together with control of diabetes, obesity and cholesterol.
Frequently asked questions
Can hormonal hypertension be cured?
When the cause is found and treated (for example removal of a unilateral aldosterone-producing adenoma), blood pressure may normalise or become easier to control.
Should I stop my medicines before hormone tests?
Never stop medication on your own; any adjustment will be planned by your physician.
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